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Iles et al, (7) evaluated the effect of clinical experience on pretest probability calculated by Wells and Geneva score.
Usefulness of clinical prediction rules, D-dimer, and arterial blood gas analysis to predict pulmonary embolism in cancer patients
We hope to continue in the long term with the new referral procedure which provides practical real-life support of the recent ACCP statement: "In patients who have a low pretest probability of VTE, as defined by the Wells prediction criteria, a negative, high-sensitivity D-dimer assay for VTE has sufficiently high negative predictive value to reduce the need for further imaging studies".
Are too many compression ultrasounds being performed for acute lower limb deep venous thrombosis in tertiary inpatients?
Having taken approval from hospital research ethical committee and informed consent, patients presenting into emergency department of AFIC, with suspicion of acute coronary syndrome, were categorized into low, intermediate and high pretest probability of acute coronary syndrome, based on history, examination, findings of initial ECG and results of cardiac biomarkers (Troponin T or CK MB).
CORONARY CT ANGIOGRAM IN THE ASSESSMENT OF SUSPECTED ACUTE CORONARY SYNDROME
sup][1],[2],[3],[4],[5],[6] As a result, in 2013 European Society of Cardiology Guidelines on the Management of SCAD (2013G), [sup][7] importance was given to systematical testing with the consideration of pretest probability and the updated Diamond-Forrester model (UDFM) [sup][8] was recommended as the clinical algorithm.
Impact of Clinical Guideline Recommendations on the Application of Coronary Computed Tomographic Angiography in Patients with Suspected Stable Coronary Artery Disease
For a patient with a solid nodule >8 mm to 3 cm, ACCP guidelines suggest that physicians estimate the pretest probability of malignancy qualitatively using their clinical judgment and/- or quantitatively by using a validated model, such as the Mayo model described above.
Pulmonary nodule on x-ray: an algorithmic approach
13) Our results suggest that AFB PCR would be most judiciously used as a supplemental test when there is a high pretest probability of mycobacterial infection (ie, histopathology with an appropriate inflammatory response with AFB present, a positive AFB smear, or clinical suspicion).
Acid-fast Smear and Histopathology Results Provide Guidance for the Appropriate Use of Broad-Range Polymerase Chain Reaction and Sequencing for Mycobacteria
Therefore the clinical profile of the patient and the pretest probability are important in assessing the test result.
Clinical implications of ST segment time-course recovery patterns during the exercise stress test
On the other hand, providers may consider that the hazard of potentially missing MI far outweighs any possible benefit from deferring troponin testing, even if the pretest probability of ACS is low.
Overriding concerns: the role of electronic medical record-based best practice alerts in reducing unnecessary laboratory testing
Clinical practice guidelines indicate that the potential harms of CT angiography outweigh the benefits for patients with a low pretest probability of pulmonary embolism.
Choosing Wisely means fewer CTs amid low risk
HIV/heart experts advise first figuring the pretest probability that a person has CHD.
When and how to screen for cardiovascular disease risk in people with HIV
This is because the level of clinical suspicion or pretest probability may be low in this racial group.
Indians have narrower blood vessels--international expert
Tips for teachers of evidence-based medicine: clinical prediction rules (CPRs) and estimating pretest probability.
Impact of probability estimation on frequency of urine culture requests in ambulatory settings

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