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Stress ECHO is appropriate for symptomatic patients with an intermediate pretest probability of CAD and contraindication to regular treadmill stress testing.
Cardiac CT, MR, SPECT, ECHO, and PET: What test, when?
The effect of pretest probability on the utility of the RF is demonstrated in Table 1.
Diagnostic tests for rheumatic disease: clinical utility revisited
This is particularly true with patients whose symptoms and exposure history may suggest a low likelihood of metal toxicity; if the pretest probability of disease is low, the probability that a positive test is a false positive result can become substantial (18).
The pitfalls of hair analysis for toxicants in clinical practice: three case reports. (Grand Rounds in Environmental Medicine)
Receiving FDA clearance for the expanded use for this assay is extremely important to Dade Behring because it provides another important tool for physicians to utilize, along with pretest probability assessment, as an aid in the diagnosis of venous thromboembolism (DVT or PE).
Dade Behring Receives FDA Clearance for Use of Its Stratus(R) CS Acute Care(TM) D-dimer Assay as an Aid in the Diagnosis of Venous Thromboembolism (VTE) (Deep Vein Thrombosis or Pulmonary Embolism)
In this case series, CTCA was able to accurately diagnose single-vessel and multivessel disease despite normal MPI scans in a population with a moderate pretest probability of CAD.
Complementary utility of multislice computed tomographic coronary angiography for detection of high-grade lesions in patients with negative stress myocardial perfusion imaging
Furthermore, since SARS infections would likely make up a minute fraction of FRIs circulating among the general population, the pretest probability, and thus the positive predictive value of RT-PCR tests, would be extremely low, even if future generation assays had better test sensitivity and specificity.
Managing febrile respiratory illnesses during a hypothetical SARS outbreak
Bronchoscopy was selected most frequently by physicians as a group as the first diagnostic test to be performed for all of the simulations except simulations 1 (peripheral lesion <2 cm, pretest probability of malignancy 10%) and 4 (peripheral lesion 2-5 cm, pretest probability of malignancy 10%).
Estimation of performance and sequential selection of diagnostic tests in patients with lung lesions suspicious for cancer. (Original Articles)
Utilization of pretest probability assessment, together with the Dade Behring Advanced D-Dimer assay, aids in the diagnosis of VTE.
Dade Behring Receives FDA Clearance for Use of Its Advanced D-Dimer Assay as an Aid in the Diagnosis of Venous Thromboembolism -- Deep Vein Thrombosis or Pulmonary Embolism
We conclude that clinical actions for HD patients could be based on a relatively small NT-proBNP change between 2 consecutive results, depending on the pretest probability of a congestive cardiac event.
Week-to-week biological variation in the n-terminal prohormone of brain natriuretic peptide in hemodialysis patients and healthy individuals
Start with high-sensitivity D-dimer measurement, not imaging, for patients with low pretest probability of venous thromboembolism (ACP).
Primary care groups take aim at needless procedures
Commercially available serologic assays to diagnose hepatitis E are not very sensitive or specific, and results must be interpreted based on the pretest probability of hepatitis E infection, he said.
Severe disease in pregnancy typical of hepatitis E infection
In contrast, under circumstances when testing is performed at relatively high pretest probability (for example, in a heavily contaminated building), a negative test result will only be convincing if the sensitivity of the system is very high.
Evaluating detection and diagnostic decision support systems for bioterrorism response

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