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Is there a dark side to long-term proton pump inhibitor therapy?
Proton pump inhibitors (PPIs) are among the most commonly used medications for the treatment of upper gastrointestinal disorders [1], and one of the most frequently prescribed classes of drugs in the world [2], because of their high effectiveness in decreasing gastric acid production and seemingly low toxicity.
Chronic use of proton pump inhibitor drugs can severely impair absorption of calcium, magnesium, iron and certain vitamins.
Proton pump inhibitors used for stress ulcer prophylaxis alter the gastric pH and may also be a contributor to this condition.
Almost two thirds of these veterans (64%) had taken a protease inhibitor, 41% had taken Vi-read, 36% had taken a proton pump inhibitor, and 21% had used a corticosteroid (like prednisone).
In this study healing rate of chronic duodenal ulcer with this combination of herbal medicines was compared with the standard treatment of proton pump inhibitor alone for H.
Try proton pump inhibitors (such as Prilosec) taken once or twice daily
A favorable response to therapy with a proton pump inhibitor (PPI) often is used as confirmation of the diagnosis (the PPI test).
16-17) Concomitant use of a proton pump inhibitor or sucralfate may also provide partial relief of symptoms.
In a 12-month study of 85 patients who received the Enteryx implant, about two-thirds were able to discontinue use of proton pump inhibitors, and 9% could reduce the dose by at least half, the FDA said.
to treat acid-related disorders (such as gastroesophageal reflux disease [GERD], erosive esophagitis, active benign gastric ulcers and other conditions associated with overproduction of stomach acid), Prevacid is the first proton pump inhibitor (PPI) available in this formulation.