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Related to pyrimidine bases: Purine nucleotides
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The latest reactions "provide a plausible route to the pyrimidine bases required in a [primitive] RNA world," the two state.
Patients with a defect in one of the enzymes of the pyrimidine degradation pathway can be diagnosed by an aberrant excretion profile of the pyrimidine bases and their degradation products in urine (1).
Since UV-B is known to affect adjacent pyrimidine bases on the DNA by linking them to form dimers, Harlow et al.