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Each of these strains had been found during routine surveillance in Nicaragua, where RotaTeq was introduced in 2006, suggesting reassortment of the vaccine strain with circulating wild-type strains.
The H1N1 pandemic of 2009 is a good example in which the pandemic virus was a result of multiple reassortments between avian, human, and swine influenza viruses in pigs (2).
The investigators noted that resistance-conferring mutations in an influenza A virus can occur as a result of drug selection, spontaneous mutation, or genetic reassortment with another drug-resistant influenza A virus (J.
As Time magazine described it, Pigs make particularly good biological mixing bowls since they can be infected by bird-, swine- and human-flu viruses and provide a hospitable environment for the viruses to swap genes and create entirely new strains in a process called reassortment.
Reassortment is responsible for the repackaging errors that, in part, created the H1N1 pandemic influenza.
This phenomenon, called reassortment, is one of two possible phenomena that lead to "antigen shift," which results in immunologically unique viruses that produce pandemic influenza strains.
It is therefore not too surprising that a novel swine influenza virus arose as a result of the exchange of genetic material, referred to as reassortment, from influenza viruses from swine, avian and human sources.
They have the unique distinction of having segmented genome which permits them reassortment in their genetic structure resulting in evolution of new subtypes.
The types are susceptible to reassortment, each reassortment taking on different qualities.
Dr Mason said, "We have been very fortunate in the timing of this because, where pandemic strains have emerged in the past, it has been through a reassortment of two viruses, where one person or an animal has become infected with two different strains with the ability to mix.
This reassortment could result in a combination virus that has the human flu's ability to spread and the bird flu's ability to kill.
Like the Killer Asian Flu, the Nigerian Virus would result from a completely new strain of H5N1, a so-called reassortment of the bird flu virus.