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Criteria of the Council of State and Territorial Epidemiologists (2009) met by patient with confirmed case of congenital rubella * Criteria met by Criteria case-patient Clinical criteria Congenital heart disease ([dagger]) Yes Microcephaly Yes Developmental delay Yes Hepatosplenomegaly Yes Purpura No Cataracts/congenital glaucoma No Hearing impairment No Pigmentary retinopathy No Jaundice No Meningoencephalitis No Radiolucent bone disease No Laboratory criteria Demonstration of rubella IgM Yes Persistent rubella antibody in an infant Yes Positive rubella RT-PCR Yes Isolation of rubella virus No * RT-PCR, reverse transcription PCR.
Prevalence of rubella virus and cytomegalovirus infections in suspected cases of congenital infections.
gondii, rubella virus, HSV1, HSV2, and CMV as measured by Abbott IMx assay, Sigma enzyme immunoassay (EIA), and Zeus EIA.
Manual for the laboratory diagnosis of measles and rubella virus infection, 2nd ed [cited 2010 Nov 22].
In nine out of 10 pregnancies where a woman is infected with the rubella virus, the unborn child will develop complications - sometime multiple complications and defects.
At least one month should elapse between a dose of a measles-containing vaccine, such as M-M-R(R) II (Measles, Mumps, and Rubella Virus Vaccine Live), and a dose of PROQUAD.
Many other febrile exanthematic diseases caused by pathogens other than measles virus, such as enterovirus, rubella virus, parvovirus B19, human herpesvirus-6, or Kawasaki syndrome, could have symptoms similar to measles and be misdiagnosed (6-8).
The rubella virus is spread by contact with discharges from the nose or throat.
So far, they have developed products for Down's syndrome screening (detecting AFP and hCG), blood bank (detecting HIV, HBV, HCV, and Syphilis), and ToRCH diagnosis (detecting Toxoplasma gondii, Rubella virus, Cytomegalovirus, and Herpes Simplex Virus Types 1 and 2).
2ng/mL), as well as a reduced process to check the purity of Rubella virus (1 hour assay vs.
These samples, which are distinguishable from saliva samples, contain mucosal cells that enable detection of the rubella virus by PCR.