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Related to saquinavir: ritonavir, nelfinavir, Saquinavir mesylate
See: deterrent
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Results from this study revealed that ritonavir 800 mg was administered with saquinavir 800 mg.
Unboosted saquinavir has poor bioavailability and requires ritonavir boosting.
The FDA approves new formulation of saquinavir (Fortovase, a soft-gel formulation designed to improve absorption in the body).
Table 1 Drugs whose metabolism is inhibited and bioavailability increased by grapefruit juice (6,7) Anti-hypertensive Calcium channel blockers FELODPINE ('Agon'; 'felodur'; 'Plendil' NIFEDIPINE ('Adalat'; 'Nyefax') NISOLDIPINE NITRENDIPINE NIMODIPINE ('Nimotop') Certain HMG CoA Reductase inhibitors SIMVASTATIN ('Lipex'; 'Zocor') LOVASTATIN ATORVASTATIN ('Lipitor') Immunomodifiers CYCLOSPORIN ('Neoral') TACROLIMUS ('Prograf') An Anti-convulsant CARBAMAZEPINE ('Tegretol') Certain Benzodiazepine sedatives MIDAZOLAM ('Hypnovel') TRIAZOLAM ('Halcion') Certain Anti-viral agents INDINAVIR ('Crixivan') SAQUINAVIR ('Invirase'; 'Fortovase') GI Motility stimulant CISAPRIDE ('Prepulsid') An Azopirone Anxiolytic BUSPIRONE ('Buspar') (9)
Predictive value of response at 12 and 24 weeks for durability of response in a study of the soft gelatin capsule formulation of saquinavir (SQV-SGC) plus two nucleosides in treatment-naive HIV-1-positive patients.
It is unclear why garlic affects saquinavir levels, but it is advised that patients taking saquinavir avoid concurrent garlic intake.
Simultaneous determination of the HIV protease inhibitors indinavir, amprenavir, saquinavir, ritonavir, nelfinavir and the nonnucleoside reverse transcriptase inhibitor efavirenz by high-performance liquid chromatography after solid-phase extraction.
New anti retro-viral drugs, such as Indnavir, Ritonavir and Saquinavir, are really helping patients.
The drugs - saquinavir and two types of ritonavir - are known as protease inhibitors.
Supply framework Bevacizumab (DOE), Saquinavir (DOE), Phytomenadione (DOE) as a single agent and Ganciclovir (DOE) Agreement.
Level 1 interactions were between (i) indinavir and lanzoprazole, omeprazole and simvastatin; (ii) ritonavir and simvastatin, digoxin and fentanyl; and (iii) saquinavir and fentanyl.
The RAINBOW - COHORT: successful initiation/switch with/to the new saquinavir 500mg formulation - first results from Germany.