This showed that in humans, the number of
satellite cells correlated strongly with changing serum estrogen levels.
Lying low but ready for action: the quiescent muscle
satellite cell. FEBS Journal.
On the other hand, in the satellite cells-dependent mechanism, quiescent
satellite cells become activated, proliferate and eventually, fuse with myofibers, or fuse to each other to form new myofibers.
Concurrent aerobic exercise interferes with the
satellite cell response to acute resistance exercise.
(2008) Estrogen influenes
satellite cell activation and proliferation following downhill running in rats.
Yamanouchi et al., "High concentrations of HGF inhibit skeletal muscle
satellite cell proliferation in vitro by inducing expression of myostatin: a possible mechanism for reestablishing
satellite cell quiescence in vivo," American Journal of Physiology-Cell Physiology, vol.
MyoD, myogenin, and desmin-nls-lacZ transgene emphasize the distinct patterns of
satellite cell activation in growth and regeneration.
These cells were first identified by Mauro in 1961 as quiescent cells located between the basal lamina and sarcolemma of myofibers, known as
satellite cells [2].
Booth, "Multiple signaling pathways mediate LIF-induced skeletal muscle
satellite cell proliferation," American Journal of Physiology Cell Physiology, vol.
An autoradiographic study of
satellite cell differentiation into regenerating myotubes following transplantation of muscles in young rats.
Kadi F, Thornell LE, 2000, Concomitant increases in myonuclear and
satellite cell content in female trapezius muscle following strength training.
However, while the use of NSAIDs has been shown to decrease perceived muscle soreness and pain associated with DOMS, they fail to impact the length or degree of muscle weakness, may be detrimental to muscle cell repair and adaptation by decreasing
satellite cell activity, and have been shown to suppress the protein synthesis response in skeletal muscle after eccentric resistance exercise."