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Scleroderma renal crisis was seen in 7% 0f patients 2 in DcSS group and 1 in LcSS group.
Keywords: Systemic scleroderma, Scleroderma renal crisis, Angiotensin-converting enzyme inhibitors.
The finding further fuels the ongoing debate over the role of angiotensin-converting enzyme (ACE) inhibitors as prophylaxis for scleroderma renal crisis (SRC), lead investigator Dr.
Previous reports identified a higher risk for maternal scleroderma renal crisis in the third trimester, but other than that have suggested that disease symptoms generally do not change or may improve during pregnancy
Although vascular interventions appear to reduce the frequency and severity of complications, such as scleroderma renal crisis and pulmonary hypertension, current therapies generally target the immune component of SSc in a non-selective fashion and have largely failed as diseases-modifying interventions.