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Related to soluble transferrin receptor: ferritin
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The results of the present study suggest that the most reliable noninvasive test for identifying iron deficiency in patients with coronary artery disease is serum soluble transferrin receptor.
Increased erythropoietic activity causes TfR synthesis to be upregulated and thereby increase the soluble transferrin receptor (sTfR) level.
Soluble transferrin receptor (sTfR) measurements (5-14) have enabled efficient detection of early iron-deficiency anemia (IDA), the treatment of which is essential, especially during phases of psychomotor development, rapid growth, and pregnancy (15-18).
The initial focus of the agreement will serve to expand Beckman Coulter's leadership position in Anemia testing to include Erythropoietin, a principal cytokine factor regulating red blood cell production, and Soluble Transferrin Receptor (STFR), which is considered the best indicator of iron deficiency.
When a CHr <28 pg was used for identification of ID and FID in anemic patients, the values of ferritin, soluble transferrin receptor (sTfR), and the sTfR-F index (sTfR/ log ferritin) (4) performed significantly better in patients without APR [based on a C-reactive protein (CRP) cutoff of 5 mg/L].
The introduction of new laboratory tests, especially soluble transferrin receptor (sTfR), has enabled the identification of storage iron depletion, iron-deficient erythropoiesis, iron deficiency anemia (IDA), and functional ID as readily distinguishable clinical conditions (1-5).
The soluble transferrin receptor (sTfR) has been introduced as a promising new diagnostic tool for differentiating between iron deficiency anemia (IDA) and anemia of chronic disease (ACD) (1-3).
Because the soluble transferrin receptor (sTfR) concentration is not influenced by acute-phase reactions, it remains within reference values in patients with anemia of chronic disease.

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