Laryngeal spindle cell
carcinoma: A population-based analysis of incidence and survival.
The tumour cells are composed of uniform population of monomorphic spindle cells
arranged in storiform pattern with mitotic figures not exceeding 5 per 10 HPF.13 The American Joint Committee on Cancer has not established a staging system for Dermatofibrosarcoma Protuberans (DFSP).
The important diagnostic issues include (1) distinguishing spindle cell
squamous cell carcinoma and malignant melanoma from true sarcoma, (2) discriminating between benign spindle cell
lesions and malignancies, and (3) classifying histologic types and subtypes.
Bcg induced mycobacterial spindle cell
pseudotumor in an infant.
It is widely reported that diagnostic difficulties can exist particularly in the distinction between poorly differentiated cutaneous spindle cell
squamous cell carcinoma (scSCC) and AFX [3, 5, 6].
Histologic sampling offered a definitive diagnosis and further characterized the tumor as the spindle cell
variant of RMS.
Microscopic examination shows a mesenchymal tumor dominated by well demarcated fascicular proliferations of myofibroblastic spindle cells
admixed with plasma cells, lymphocytes, and histiocytes.
Caption: Figure 1: Picture shows that spindle cell
proliferation admixed with inflammatory cells (HE x40).
Caption: Figure 3: Histology with H&E staining and high-power magnification showing spindle cells
suggestive of monophasic variant of synovial sarcoma.
Later, Perkins and Weiss  proposed the terms SCH for solitary lesions and "spindle cell
hemangiomatosis" for multifocal lesions.
Key Words: Spindle cell
tumor, neural tumor, oral cavity, S100, schwannoma, neurofibroma, traumatic neuroma, MPNST, GCT.
Among these most accepted theory is that there is a transformation from the squamous cell carcinoma component into a spindle cell