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Maternal natural killer cells and macrophages facilitate deep trophoblastic invasion into myometrial segments and promote extensive spiral artery remodeling.
Cases may not be responsive to human albumin 25-50 g due to small placenta, edema of the villi, or spiral artery avulsion," said Dr.
The etiology of the disease is still unknown, although research suggests that the trophoblast is unable to effectively invade the decidua or to modify the spiral artery walls (3).