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In summary, this study shows that children adopted from Ethiopia who lived in malaria-endemic regions of Ethiopia or had past or current splenomegaly are at risk for asymptomatic P.
8,9] The anemia and splenomegaly could have been pointers towards the diagnosis of an underlying hematological disorder.
In a subset of arbitrarily chosen cases, histologic assessment of the spleen was undertaken to examine the nature of the splenomegaly occurring in the absence of cirrhosis.
Presence of JAK2 V617F is associated with higher white cell counts, red cell counts, platelet counts, splenomegaly, and increased risk of thrombosis.
CT of the abdomen following administration of intravenous contrast material revealed splenomegaly and an indeterminate low-attenuation lesion in the right lobe (segment VI) of the liver.
Patients with JAK2 V617F mutation had higher splenomegaly (86%) as compared to the wild type (58%) but this was not statistically significant.
11) Usually clinical presentation of therapy-related CML is similar to that of de novo cases, but there are data indicating lower frequency of splenomegaly and hyperleukocytosis.
The frequency of splenomegaly is comparable with that recorded by Yee et al.
Abdominal ultrasonography showed a normal sized liver with coarse hepatic echotexture and no focal lesions, mild ascites, and splenomegaly with normal gall bladder, common bile duct, and pancreas.
MCD is a relapsing and remitting disease and the definition of an 'attack' has been proposed as a combination of fever and a raised serum C-reactive protein in the absence of other aetiology, plus three of the following symptoms: peripheral lymphadenopathy, splenomegaly, oedema, pleural effusion, ascites, cough, nasal obstruction, xerostomia, rash, central neurological symptoms, jaundice or autoimmune haemolytic anaemia [7].
There was no family history of consanguinity, splenomegaly, diabetes, or developmental delay.