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Sustained virological response to interferon-alpha is associated with improved outcome in HCV-related cirrhosis: a retrospective study.
Feld et al., "Association between sustained virological response and all-cause mortality among patients with chronic hepatitis C and advanced hepatic fibrosis," The Journal of the American Medical Association, vol.
Hernandez, "Sustained virological response correlates with reduction in the incidence of glucose abnormalities in patients with chronic hepatitis C virus infection," Diabetes Care, vol.
Durability of antiviral therapy for chronic hepatitis C after achieving sustained virological response. Korean J Hepatol 2011; 17: 180-2.
Sustained virological response to antiviral therapy reduces mortality in HCV reinfection after liver transplantation.
Data regarding socio-demographics, risk factors, treatments received, medical comorbidities, and clinical features--such as early virological response (EVR), sustained virological response (SVR), and histologic stage--were assessed and recorded.
Another study on patients who had achieved sustained virological response and were followed for 23 years showed no progression of liver disease12 and were labeled as cured of infection by their clinicians.
El Makhzangy et al., "Predictors of a sustained virological response in patients with genotype 4 chronic hepatitis C," Liver International, vol.
Those who achieved a sustained virological response after treatment exhibited a reduction in all-cause mortality >50% compared with nonresponders.
Patients that smoked marijuana every day or two found that not only did they complete the therapy, but that the marijuana even made it more effective in achieving a "sustained virological response," which is the gold standard in therapy, meaning there was no sign of the virus left in their bodies.
On day 29, all patients were switched to treatment with BI 201335 and PegIFN/RBV for an additional 44 weeks per the defined study protocol, and will be followed to evaluate sustained virological response.
A substandard interferon fails to create the required Sustained Virological Response (SVR) in the patients body and causes the Genome 2 or 3 type virus to develop resistance against drugs and it transforms into the Genome 1 type.