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Keywords: Abruptio placenta, APH (antepartum hemorrhage), Calcification, Cotyledon, Diameter in centimeters, Fibrinoid necrosis, Syncytial knots, Weight in grams.
The present study showed marked decrease in placental weight, increase in placental infarcts, and syncytial knot hyperplasia at decreasing levels of maternal hemoglobin.
All the important histological features such as fibrin deposition, villous pattern, syncytial knots, infarction, calcification, stromal fibrosis were noted in placentae.
Histological variables evaluated were villous maturation, decidual arteriopathy, infarction, accelerated intervillous maturation, cytotrophoblastic proliferation, stromal oedema, stromal fibrosis, and syncytial knots. Other eventual findings were noted separately.
Increased number of syncytial knots indicates a degenerative process as a response to local hypoxia.
Chorangiosis (presence of more than 5 vessels per villi), calcification, syncytial knots formation (excessive amounts and formation of trophoblastic nuclear out pouching) are also important signs of altered placental texture.14 These increased hypoxic parameters in placental tissues are associated with increased in fetal and maternal mortality and morbidity.
Described placental enlargement may result in increase syncytial knots' ripping off, that undissolved in maternal blood may undergo necrosis and leed to preeclamptic symptoms [3].
A normal placenta shows heterogeneous maturation because better-oxygenized centers of cotyledons (placentones) are less mature (larger chorionic villi with less syncytial knots) than are their peripheral parts, where the less-oxygenized blood returns toward the uterus.
b--Determine any possible relationship of the indices of body shape and body composition at birth to maternal haemoglobin concentrations and haematocrit values at the end of gestation, placental morphology (placental weight, incidences of syncytial knots and cytotrophoblastic cells and foetal capillary numbers) and fetal haemoglobin concentrations and haematocrit values at birth.
Furcate placenta has greater volume than normal villi, villous trophoblast and syncytial knots. Furcate placenta is more prone to early delivery because they are heavier more voluminous villi with more trophoblast & syncytial knots.
They achieved moderate-to-substantial agreement for a variety of indicators of inflammation, presence of macrophages with pigment and indicators of villous maturity, increased syncytial knots, and maternal vasculopathy.
Syncytial Knots: In the present study we found significantly higher syncytical knot counts about 66.67% cases and 18.75% Infants had neonatal as PHYSCIA and 35% had low birth weight.