target

(redirected from target cell)
Also found in: Dictionary, Thesaurus, Medical, Financial, Encyclopedia, Wikipedia.
Related to target cell: poikilocytosis, basophilic stippling
Mentioned in ?
References in periodicals archive ?
The activity of numerous therapeutic antibodies is mediated in part by immune-mediated effector cell function following binding of the variable regions of the antibody to a specific antigen on the surface of target cells and the interaction of the Fc moiety of the antibody with an Fc receptor on an immune effector cell [1].
A Novel System for the Quantification of the ADCC Activity of Therapeutic Antibodies
MP-mediated increases in cAMP levels in the near-membrane compartment of target cells is sufficient to activate known cAMP effectors.
Intercellular signaling by cyclic AMP-containing microparticles
The cell line K562, an NK-sensitive tumoral human erythroleukemia cell line, was used as target cells. Cells were grown in RPMI-1640 (Gibco-BRL, UK) supplemented with 10% fetal bovine serum (FBS, Dutscher, France) and cultured for 24 h before cytometric analysis.
Differences in lymphocyte subpopulation count and function in cord, maternal and adult blood / Kordon kani, maternal ve eriskin kanda sayisal ve fonksiyonel lenfosit alt grup farkliliklari
In its simplest form, a negative feedback system consists of a hormone inducing a response in a target cell, and the response in turn inhibiting further release of the hormone.
Chapter 7: Principles of reproductive endocrinology
(6,7) These agents target the intracellular domain of the tyrosine kinase receptor within the cytoplasm of the target cell and compete with ATP to bind on the kinase domain.
Epidermal growth factor receptor treatment
The K-562 target cells were washed twice in complete Dubelco modified Eagle medium (DMEM) medium (DMEM supplemented with 2 mM L-glutamine, 1 mM sodium pyruvate, 0.1 mM minimal nonessential amino acids, 5 units/mL penicillin, 50 mg/mL streptomycin (media and supplements from Gibco Laboratories Life Technologies Inc., Grand Island, New York) and 10% fetal calf serum (HyClone Laboratories Inc.
Development of assays to evaluate cellular immune functions in the American lobster (Homarus americanus)
Chemists and materials scientists have been creating virus-size structures to temporarily encase and protect genetic material, diffuse nimbly through three-dimensional tissue, zero in on target cells, enter those cells, and then release genetic cargoes at the proper locations.
Delivering the goods: gene therapy without the virus
The "corrected" gene undergoing transfer into the affected cell is called a "transgene." A transgene requires delivery into the affected individual's body to reach the target cells. Transgene delivery into target cells requires a carrier or a vector.
Gene Therapy: Pharmaceutical Alteration of the Human Genome
Anderson's view, this should come only after animal research had demonstrated some key points: that the new gene could be put into the intended target cells and would remain there capable of functioning that the body would regulate the transplanted gene appropriately and that it would not harm the cell.
Curing disease through human gene therapy
Stefano Pluchino from the Cambridge Stem Cell Institute said the tiny vesicles in stem cells contain molecules like proteins and nucleic acids that stimulate the target cells and help them to survive: they act like mini "first aid kits".
How stem cells repair damage
"It allows almost any protein to diffuse into a target cell. A few hundred molecules of perforin is sufficient to obliterate any cell."
Study unearths well-kept secret of our immune system's success
The resulting fusion protein may be used to deliver the biologically active ligand to a specific target cell or tissue.
Merck Patent GmbH obtains United States patent

Legal browser ?
Full browser ?