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If transaction log occupies all the free disk space and database becomes unavailable, we probably do not have time to wait for the log backup to complete, but we rather just want to truncate and shrink the log as soon as possible.
The combination tC means truncate a cube; that is, cut off the corners of a cube to form a new solid with six octagonal and eight triangular faces.
21/28 Nature, they report that each of those families harbors one of five mutations that truncate the protein produced from BRCA2's instructions.