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The most common is represented by the flu-like syndrome, whose symptoms (e.g., headache, fever, and ubiquitary arthralgia) are prominent at the beginning of the therapy, although they decrease progressively, in frequency and severity, when the treatment is prolonged [7].
On January 19th 2014, a 80-year old man presented with abdominal pain, weakness, and fever (39.8[degrees]C) on January 21st 2014, which were due to a prostate carcinoma (3.5 cm diameter) and extended ubiquitary skeletal metastases, but without hepatic metastasis as determined by MRT on January 29th 2014.
It is important to note that possible contaminations through ubiquitary traces cannot be completely excluded.